US Patent Issued to Institute of Microbiology, Chinese Academy of Sciences on July 28 for "Screening and antitumor use of KRAS mutation specific T cell receptor" (Chinese Inventors)

ALEXANDRIA, Va., July 28 -- United States Patent no. 12,692,298, issued on July 28, was assigned to Institute of Microbiology, Chinese Academy of Sciences (Beijing).

"Screening and antitumor use of KRAS mutation specific T cell receptor" was invented by Fu Gao (Beijing), Shuguang Tan (Beijing) and Dan Lu (Beijing).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure provides two specific T cell receptors targeting a G12V or G12C mutant epitope of a KRAS gene, and an anti-tumor use thereof. Each of the two T cell receptors consists of an Alpha peptide chain and a Beta peptide chain. Further provided are an antigen binding fragment of the T cell receptors, a nucleic acid encoding the T cell rec...