US Patent Issued to Institute of Biophysics, Chinese Academy of Sciences on March 24 for "Method for capturing RNA in situ higher-order structures and interactions" (Chinese Inventors)

ALEXANDRIA, Va., March 24 -- United States Patent no. 12,584,160, issued on March 24, was assigned to Institute of Biophysics, Chinese Academy of Sciences (Beijing).

"Method for capturing RNA in situ higher-order structures and interactions" was invented by Yuanchao Xue (Beijing), Zhaokui Cai (Beijing) and Changchang Cao (Beijing).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention discloses a method for capturing an RNA in situ higher-order structure and interaction. The method includes: fixing protein-mediated RNA-RNA interaction in cell or tissue; performing membrane permeabilization while keeping the cell intact; degrading free RNA; labeling the 3' end of the RNA with pCp-biotin and perfo...