US Patent Issued to Insitro on June 23 for "Synthon embeddings for modeling DNA-encoded libraries" (California Inventors)

ALEXANDRIA, Va., July 15 -- United States Patent no. 12,665,048, issued on June 23, was assigned to Insitro Inc. (South San Francisco, Calif.).

"Synthon embeddings for modeling DNA-encoded libraries" was invented by Benson Chen (Palo Alto, Calif.), Mohammad Muneeb Sultan (San Francisco) and Theofanis Karaletsos (San Francisco).

According to the abstract* released by the U.S. Patent & Trademark Office: "Embodiments of the disclosure involve modeling DEL data using factorized molecular representations (e.g., hierarchical mono-synthon and di-synthon building blocks), which capitalizes on the inherent hierarchical structure of these molecules. Using the factorized molecular representations, machine learning models are trained to learn latent ...