ALEXANDRIA, Va., March 24 -- United States Patent no. 12,583,838, issued on March 24, was assigned to INSILICO MEDICINE HONG KONG Ltd. (Hong Kong).
"Analogs for the treatment of disease" was invented by Aleksandrs Zavoronkovs (Hong Kong), Aleksandr Aliper (Ramenskoye, Russia), Vladimir Aladinskiy (Kaliningrad, Russia) and Andrey Kukharenko (Moscow).
According to the abstract* released by the U.S. Patent & Trademark Office: "The disclosure provides TNIK and/or MAP4K4 kinases inhibitors for the treatment of disease. In one aspect, disclosed herein are kinase inhibitors having a structure of Formula (A), (A*), (I), (IIA), or (IIB). Further described herein are pharmaceutical composition comprising these compounds and methods of using these c...