US Patent Issued to INDUSTRIALE CHIMICA on April 21 for "Process for the preparation of drospirenone as a fine powder through a double change of crystalline form" (Italian Inventors)

ALEXANDRIA, Va., April 21 -- United States Patent no. 12,606,591, issued on April 21, was assigned to INDUSTRIALE CHIMICA S.R.L. (Milan).

"Process for the preparation of drospirenone as a fine powder through a double change of crystalline form" was invented by Roberto Lenna (S. Giorgio su Legnano, Italy) and Michele Baldrighi (Milan).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention refers to a process for the industrial-scale preparation of 17Beta-hydroxy-6Beta,7Beta; 15Beta,16Beta-dimethylene-3-oxo-17Alpha-pregn-4-ene-21-carboxylic acid Gamma-lactone, known by the common name of Drospirenone, in the form of a fine powder without the use of mechanical grinding or micronization techniques, ...