ALEXANDRIA, Va., July 7 -- United States Patent no. 12,673,951, issued on July 7, was assigned to Impact Therapeutics (Shanghai) Inc (Shanghai).

"Substituted pyrazoloquinazolinone compounds and application thereof" was invented by Sui Xiong Cai (Shanghai), Ye Edward Tian (Shanghai) and Xiaozhu Wang (Nanjing, China).

According to the abstract* released by the U.S. Patent & Trademark Office: "A compound of formula I, or a stereoisomer, tautomer, N-oxide, hydrate, isotope-substituted derivative, or solvate thereof, or a pharmacologically acceptable salt thereof, or a mixture thereof, of a prodrug thereof. The compound of formula I is a kinase inhibitor which can be used for treating clinical disorder caused by DDR deficiencies, such as cance...