ALEXANDRIA, Va., April 21 -- United States Patent no. 12,606,607, issued on April 21, was assigned to Immunocore Ltd. (Abingdon, Great Britain).
"T cell receptors" was invented by Conor Hayes (Abingdon, Great Britain), Linda Hibbert (Abingdon, Great Britain), Nathaniel Ross Liddy (Abingdon, Great Britain), Tara Mahon (Abingdon, Great Britain) and Marine Raman (Abingdon, Great Britain).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to T cell receptors (TCRs) that bind the HLA-A*02 restricted peptide GVYDGREHTV (SEQ ID NO: 1) derived from the germline cancer antigen MAGE A4. Said TCRs may comprise non-natural mutations within the alpha and/or beta variable domains relative to a nat...