US Patent Issued to ICHIMARU PHARCOS on Oct. 6 for "VIPR2 antagonist peptide" (Japanese Inventors)

ALEXANDRIA, Va., Oct. 6 -- United States Patent no. 12,753,206, issued on Oct. 6, was assigned to ICHIMARU PHARCOS Co. LTD. (Gifu, Japan).

"VIPR2 antagonist peptide" was invented by Kotaro Sakamoto (Gifu, Japan) and Yukio Ago (Hiroshima, Japan).

According to the abstract* released by the U.S. Patent & Trademark Office: "A VIPR2 antagonist peptide includes a cyclic peptide comprising an amino acid sequence represented by formula (17): c[X1-Pro-X3-Tyr4-Leu5-Pro6-c(X7-X8-Leu9-Cys10]-X11)-X12-X13 (17), wherein X1 denotes cysteine, Mpa (3-mercaptopropionic acid), or D-cysteine; X3 denotes N-methylglycine, N-methylalanine, 2-azetidine-2-carboxylic acid, proline, hydroxyproline, 3,4-dehydroprolone, pipecolic acid, serine, or lysine; X8 denotes t...