US Patent Issued to Icahn School of Medicine at Mount Sinai on Oct. 20 for "Compositions and methods of treatment of vision loss through generation of rod photoreceptors from Muller glial cells" (New York Inventor)

ALEXANDRIA, Va., Oct. 21 -- United States Patent no. 12,766,167, issued on Oct. 20, was assigned to Icahn School of Medicine at Mount Sinai (New York).

"Compositions and methods of treatment of vision loss through generation of rod photoreceptors from Muller glial cells" was invented by Bo Chen (New York).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention provides methods and compositions for inducing differentiation of Muller glial cells into rod photoreceptors through a two-step process of inducing Muller glial cell proliferation by increasing WNT signaling effectors in the Muller glial cell and then directed differentiation into a rod photoreceptor through activation of rod-specific photo...