ALEXANDRIA, Va., Aug. 12 -- United States Patent no. 12,703,697, issued on Aug. 11, was assigned to Icagen LLC (Emeryville, Calif.).

"BCAT modulation" was invented by Paul R. August (Durham, N.C.), Margaret Kenney (Durham, N.C.), Jacques Mauger (Durham, N.C.), Mark Drew (Durham, N.C.) and Weixi Kong (Durham, N.C.).

According to the abstract* released by the U.S. Patent & Trademark Office: "This disclosure relates to, in part, the treatment of an organic acidemia in a subject in need thereof via administration of a therapeutically effective amount of compounds that inhibit BCAT2. The disclosure also relates to, in part, methods for identifying a candidate compound for treatment of organic acidemias such as maple syrup urinary disease, meth...