ALEXANDRIA, Va., March 17 -- United States Patent no. 12,576,027, issued on March 17, was assigned to IBSA INSTITUT BIOCHIMIQUE SA (Lugano, Switzerland).

"Diclofenac topical formulation with a high absorption rate" was invented by Nadia Puppini (Lugano, Switzerland), Valentina Nicolini (Lugano, Switzerland) and Tiziano Fossati (Lugano, Switzerland).

According to the abstract* released by the U.S. Patent & Trademark Office: "Pharmaceutical compositions for topical use containing diclofenac in the form of salt with epolamine, present at concentrations higher than 2.0% by weight are described. Such compositions provide, with respect to those currently available, a more complete absorption of the administered dose, reducing the dispersion of ...