US Patent Issued to Hoffmann-La Roche on Sept. 22 for "Process for the preparation of 2-bromo-4-(3,5-difluorophenyl)-4,5,6,7-tetrahydro-[1,2,4triazolo[1,5-apyrimidine" (Chinese Inventors)

ALEXANDRIA, Va., Sept. 24 -- United States Patent no. 12,741,969, issued on Sept. 22, was assigned to Hoffmann-La Roche Inc. (Branchburg, N.J.).

"Process for the preparation of 2-bromo-4-(3,5-difluorophenyl)-4,5,6,7-tetrahydro-[1,2,4triazolo[1,5-apyrimidine" was invented by Guocai Zhang (Shanghai) and Weichun Chen (Shanghai).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure provides a process for preparing 2-bromo-4-(3,5-difluorophenyl)-4,5,6,7-tetrahydro-5H-[1,2,4]triazolo[1,5-a]pyrimidine. In one example, a corresponding precursor compound is reacted with triphenylphosphine and an azodicarboxylate reagent in an organic solvent at a reduced temperature to form the desired triazolopyrimidi...