ALEXANDRIA, Va., Sept. 15 -- United States Patent no. 12,735,477, issued on Sept. 15, was assigned to Hoffmann-La Roche Inc. (Branchburg, N.J.).

"Antibody that binds to VEGF and IL-1BETA and methods of use" was invented by Roland Beckmann (Penzberg, Germany), Joerg Benz (Rheinfelden, Germany), Stefan Dengl (Geretsried, Germany), Christian Gassner (Penzberg, Germany), Guido Hartmann (Loerrach, Germany), Peter Michael Huelsmann (Habach, Germany), Sabine Imhof-Jung (Krailling, Germany), Kristian Hobolt Jensen (Vienna), Hubert Kettenberger (Munich), Stefan Lorenz (Iffeldorf, Germany), Joerg Moelleken (Munich) and Olaf Mundigl (Polling, Germany).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention ...