US Patent Issued to Hoffmann-La Roche on June 9 for "Amino-pyrimidine cyclo-amides" (French, German, Swiss Inventors)

ALEXANDRIA, Va., June 9 -- United States Patent no. 12,649,745, issued on June 9, was assigned to Hoffmann-La Roche Inc. (Little Falls, N.J.).

"Amino-pyrimidine cyclo-amides" was invented by Angelica Beurier (Courtavon, France), Luke Green (Basel, Switzerland), Christian Kramer (Lorrach, Germany), Dmitry Mazunin (Grenzach-Wyhlen, Germany), Emmanuel Pinard (Linsdorf, France) and Hasane Ratni (Habsheim, France).

According to the abstract* released by the U.S. Patent & Trademark Office: "The invention provides novel compounds having the general formula (I)wherein R1, R2, R3 and n are as defined herein, compositions including methods of making the compounds and using the compounds as ATX inhibitors."

The patent was filed on Dec. 7, 2022, und...