ALEXANDRIA, Va., May 12 -- United States Patent no. 12,624,098, issued on May 12, was assigned to Hoffmann-La Roche Inc. (Little Falls, N.J.) and Genentech Inc. (South San Francisco, Calif.).

"Treatment of age-related macular degeneration and diabetic macular edema by administration of a bispecific antibody to VEGF and ANG-2" was invented by Aaron Osborne (South San Francisco, Calif.), Jayashree Sahni (Basel, Switzerland) and Robert James Weikert (Basel, Switzerland).

According to the abstract* released by the U.S. Patent & Trademark Office: "The current invention relates to the use of bispecific antibodies that bind to human vascular endothelial growth factor (VEGF) and to human angiopoietin-2 (ANG-2) for the treatment of ophthalmologic ...