ALEXANDRIA, Va., March 24 -- United States Patent no. 12,584,091, issued on March 24, was assigned to Hoffman-La Roche Inc. (Little Falls, N.J.).
"Predicting the metabolic condition of a cell culture" was invented by Wolfgang Paul (Penzberg, Germany), Arthur Mohr (Penzberg, Germany) and Sayuri Hortsch (Munich).
According to the abstract* released by the U.S. Patent & Trademark Office: "A method for predicting the metabolic state of a cell culture of cells of a specific cell type includes providing a metabolic model of a cell of the specific cell type, and performing at each of a plurality of points in time during cultivation of the cell culture, receiving measured concentrations of a plurality of extracellular metabolites and a measured c...