US Patent Issued to H. Lee Moffitt Cancer Center and Research Institute on June 2 for "Fucosylation and immune modulation in cancer" (Florida Inventor)

ALEXANDRIA, Va., June 2 -- United States Patent no. 12,642,809, issued on June 2, was assigned to H. Lee Moffitt Cancer Center and Research Institute (Tampa, Fla.).

"Fucosylation and immune modulation in cancer" was invented by Eric Le-Lau (Tampa, Fla.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed are methods for treating a cancer and/or modulating immune CD4+ T cell mediated therapies comprising administering to a subject a fucose. In one aspect, disclosed herein are methods of modulating major histocompatibility complex II human lymphocyte antigen (HLA)-DRB 1 expression on the surface of a cell comprising contacting the cell with an agent that modulates the amount of fucosylation on the cell; wh...