ALEXANDRIA, Va., March 31 -- United States Patent no. 12,590,326, issued on March 31, was assigned to Guardant Health Inc. (Palo Alto, Calif.).
"Methods for fragmentome profiling of cell-free nucleic acids" was invented by Diana Abdueva (Orinda, Calif.).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure contemplates various uses of cell-free DNA. Methods provided herein may use sequence information in a macroscale and global manner, with or without somatic variant information, to assess a fragmentome profile that can be representative of a tissue of origin, disease, progression, etc. In an aspect, disclosed herein is a method for determining a presence or absence of a genetic aberration in ...