ALEXANDRIA, Va., July 21 -- United States Patent no. 12,688,905, issued on July 21, was assigned to GRAIL LLC (Menlo Park, Calif.).

"Method and system of cancer detection using CpG-SNP contamination markers" was invented by Onur Sakarya (Redwood City, Calif.), Christopher Chang (Palo Alto, Calif.), Ajinkya Kokate (Union City, Calif.) and Samuel S. Gross (Sunnyvale, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Methods and systems for detecting contaminated fragments in a biological sample for cancer classification are disclosed. The system identifies CpG-SNP contamination markers. The CpG-SNP contamination markers include at least one SNP that affects a CpG site. The CpG-SNP contamination markers may...