ALEXANDRIA, Va., May 12 -- United States Patent no. 12,622,887, issued on May 12, was assigned to Giuseppe Castellano (Gravina in Puglia, Italy), IPERBOREAL PHARMA SRL (Pescara, Italy) and PUERAPULIAE INVEST SRL (Bari, Italy).

"Liquid pharmaceutical compositions comprising citrate and carnitine" was invented by Giuseppe Castellano (Gravina in Puglia, Italy), Rossana Franzin (Bitonto, Italy), Alessandra Stasi (Molfetta, Italy), Fabio Sallustio (Bisceglie, Italy) and Arduino Arduini (Arogno, Switzerland).

According to the abstract* released by the U.S. Patent & Trademark Office: "A composition comprising citrate and carnitine which activates the production of the protein Klotho by renal tubule cells protecting them, thus reducing the oxidat...