ALEXANDRIA, Va., March 31 -- United States Patent no. 12,589,138, issued on March 31, was assigned to Genzyme Corp. (Cambridge, Mass.).

"Marker for acid sphingomyelinase disorders and uses thereof" was invented by Wei-Lien Chuang (Bridgewater, N.J.), Gerald F. Cox (Bridgewater, N.J.) and X. Kate Zhang (Bridgewater, N.J.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure provides methods of screening, diagnosing, monitoring and/or treating acid sphingomyelinase (ASM) disorders such as Niemann-Pick disease. In particular, the methods encompass techniques for improved diagnosis and/or treatment of an ASM disorder, for example using enzyme replacement therapy."

The patent was filed on April 2...