ALEXANDRIA, Va., Nov. 3 -- United States Patent no. 12,781,265, issued on Nov. 3, was assigned to Gen-Probe Inc. (San Diego).
"Temperature-selectable FRET cassette signaling" was invented by Michael J. Gilly (San Diego), Ankur H. Shah (San Diego) and Andrew S. Gilder (San Diego).
According to the abstract* released by the U.S. Patent & Trademark Office: "A multiplexed nucleic acid amplification and detection system useful for detecting the presence of multiple specific nucleic acid sequences or single nucleotide polymorphisms (i.e., "SNPs") in a temperature-dependent fashion using only a single fluorescence detection channel of a nucleic acid analyzer. The technique can be carried out using standard PCR instrumentation equipped for fluore...