US Patent Issued to GE Healthcare AS on Nov. 3 for "Lanthanide complex formulations" (Norwegian Inventors)

ALEXANDRIA, Va., Nov. 3 -- United States Patent no. 12,779,054, issued on Nov. 3, was assigned to GE Healthcare AS (Oslo, Norway).

"Lanthanide complex formulations" was invented by Mikkel Jacob Thaning (Oslo, Norway) and Andreas Richard Meijer (Oslo, Norway).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to a method of removal of metal ion impurities, such as calcium, from lanthanide metal complexes of macrocyclic chelators. The method uses a scavenger resin to remove metal ions, displaced from chelator, by an excess of lanthanide ions. Also provided is a method of preparation of MRI contrast agents, from the purified lanthanide metal complex, by the addition of a defined excess ...