ALEXANDRIA, Va., Feb. 17 -- United States Patent no. 12,551,581, issued on Feb. 17, was assigned to Galera Labs LLC (Creve Coeur, Mo.).
"Combination cancer immunotherapy with pentaaza macrocyclic ring complex" was invented by Robert A. Beardsley (University City, Mo.), Jeffery L. Keene (St. Louis) and Dennis P. Riley (Chesterfield, Mo.).
According to the abstract* released by the U.S. Patent & Trademark Office: "A method of treating a cancer in a mammalian subject afflicted with the cancer, includes administering to the subject an immune checkpoint inhibitor, and administering to the subject a pentaaza macrocyclic ring complex corresponding to the formula (I) below, prior to, concomitantly with, or after administration of the immune check...