ALEXANDRIA, Va., Feb. 17 -- United States Patent no. 12,551,549, issued on Feb. 17, was assigned to Fred Hutchinson Cancer Center (Seattle).

"Methods of eliciting antibodies that bind to full-length glycosylated HIV-1 ENV using multimerized ENV cores" was invented by Leonidas Stamatatos (Seattle), Andrew McGuire (Seattle), Katherine Rachael Parks (Seattle) and Matthew D. Gray (Seattle).

According to the abstract* released by the U.S. Patent & Trademark Office: "Sequential immunization strategies to guide the maturation of antibodies against the human immunodeficiency virus (HIV) are described. The sequential immunization strategies utilize an HIV envelope protein (Env) that binds germline (gl) B cells as a first (prime) immunization and a...