ALEXANDRIA, Va., June 2 -- United States Patent no. 12,643,851, issued on June 2, was assigned to FERMENTA BIOTECH Ltd. (Thane West, India).

"Vitamin D3 and its analogue Calcifediol from Ergosterol" was invented by Anupama Datla (Thane, India), Prashant Nagre (Thane, India), Jagdish Tamore (Thane, India), Manojkumar Sadanand Prabhu (Thane, India) and Sachin Vasant Kadam (Thane, India).

According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed herein is an improved and efficient process for synthesis of vitamin D3 and its analogue Calcifediol from Ergosterol. Particularly, the present invention discloses the synthesis of key intermediate 3Beta-tert-Butyldimethylsilyloxy-22-hydroxy-23,24-bisnorchola-5,7-diene (5)...