ALEXANDRIA, Va., Aug. 5 -- United States Patent no. 12,698,482, issued on Aug. 4, was assigned to ENTRADA THERAPEUTICS INC. (Boston).

"Compositions and methods for treating mitochondrial neurogastrointestinal encephalopathy" was invented by Natarajan Sethuraman (Boston), Jason Ruth (Boston), Louis A. Tartaglia (Boston), Dehua Pei (Columbus, Ohio) and Ziqing Qian (Boston).

According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed herein are compositions and methods of treating disclosure provides for compounds for use in treating Mitochondrial Neurogastrointestinal Encephalopathy Syndrome (MNGIE). In some embodiments, the compounds have cell penetrating activity and thymidine phosphorylase activity. In certain e...