US Patent Issued to Element Biosciences on April 21 for "PCR-free library preparation using double-stranded splint adaptors and methods of use" (California Inventors)

ALEXANDRIA, Va., April 21 -- United States Patent no. 12,606,819, issued on April 21, was assigned to Element Biosciences Inc. (San Diego).

"PCR-free library preparation using double-stranded splint adaptors and methods of use" was invented by Junhua Zhao (San Diego), Xiaodong Qi (San Diego) and Shawn Levy (San Diego).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure provides compositions comprising nucleic acid double-stranded splint adaptors, including kits, and methods that employ the double-stranded splint adaptors, e.g., PCR-free workflows. The double-stranded splint adaptors (200) can be used in a one-pot, multi-enzyme reaction to introduce one or more new adaptor sequences into a li...