ALEXANDRIA, Va., March 31 -- United States Patent no. 12,590,084, issued on March 31, was assigned to Eikonizo Therapeutics Inc. (Cambridge, Mass.).

"Oxadiazole HDAC6 inhibitors and uses thereof" was invented by Florence Fevrier Wagner (Ashland, Mass.) and Thomas Edward Richardson (Cary, N.C.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided herein are compounds that selectively inhibit HDAC6, a protein whose activity is associated with a variety of diseases (e.g., cancer, neurological disorders). Also provided are pharmaceutical compositions and kits comprising the compounds, and methods of treating HDAC6-related diseases and disorders (e.g., Alzheimer's disease, cancer) with the compounds in a subjec...