US Patent Issued to DUQUESNE UNIVERSITY OF THE HOLY SPIRIT on Aug. 11 for "RNA G-quadruplex structure in pre-miRNA-1229 as a therapeutic target for Alzheimer's disease and various cancers" (Pennsylvania Inventors)

ALEXANDRIA, Va., Aug. 12 -- United States Patent no. 12,703,863, issued on Aug. 11, was assigned to DUQUESNE UNIVERSITY OF THE HOLY SPIRIT (Pittsburgh).

"RNA G-quadruplex structure in pre-miRNA-1229 as a therapeutic target for Alzheimer's disease and various cancers" was invented by Mihaela Rita Mihailescu (Pittsburgh) and Joshua A. Imperatore (Canonsburg, Pa.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided is an agent that binds to a wild type or variant pre-miRNA-1229 comprising a G-quadruplex (GQ) structure, wherein binding of the agent to the wild type or variant pre-miRNA-1229 stabilizes the GQ structure of the wild type or variant pre-miRNA-1229. In some embodiments, the variant is rs2291418. P...