US Patent Issued to Duke University on March 24 for "Compositions comprising microbial polypeptides for degrading glycogen and methods for the treatment of glycogen storage diseases" (North Carolina Inventors)

ALEXANDRIA, Va., March 24 -- United States Patent no. 12,582,724, issued on March 24, was assigned to Duke University (Durham, N.C.).

"Compositions comprising microbial polypeptides for degrading glycogen and methods for the treatment of glycogen storage diseases" was invented by Priya Kishnani (Durham, N.C.), Baodong Sun (Durham, N.C.) and Jeong-A Lim (Durham, N.C.).

According to the abstract* released by the U.S. Patent & Trademark Office: "This disclosure provides isolated nucleic acid molecules comprising nucleic acid sequences encoding microbial polypeptides that are codon optimized for expression in mammalian cells, vectors comprising an immunotolerant dual promoter system, and methods using these polynucleotides and polypeptides to...