ALEXANDRIA, Va., May 19 -- United States Patent no. 12,630,852, issued on May 19, was assigned to DSM IP ASSETS B.V. (Heerlen, Netherlands).
"Modified sterol acyltransferases" was invented by Otto Martin Lehmann (Kaiseraugst, Switzerland), Harald Pichler (Graz, Austria) and Holly Stolterfoht (Graz, Austria).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention is related to modified sterol acyltransferase enzymes with improved activity and/or specificity towards acylation of the vitamin D3 precursor 7-dehydrocholesterol (7-DHC) to be used in biotechnological production of vitamin D3. The invention further relates to a host strain expressing said modified enzymes and their use in a process for p...