US Patent Issued to Dicerna Pharmaceuticals on July 7 for "Compositions and methods for modulating SCAP activity" (Massachusetts Inventors)

ALEXANDRIA, Va., July 7 -- United States Patent no. 12,674,169, issued on July 7, was assigned to Dicerna Pharmaceuticals Inc. (Lexington, Mass.).

"Compositions and methods for modulating SCAP activity" was invented by Bob Dale Brown (Littleton, Mass.), Henryk T. Dudek (Belmont, Mass.), Seongmoon Cheong (Harvard, Mass.) and Nicole Alexis Spiegelman (Somerville, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Oligonucleotides and compositions including the same are disclosed that modulate (e.g., inhibit, limit or reduce) sterol regulatory element-binding protein (SREBP) cleavage-activating protein (SCAP) activity. Methods of making and using the oligonucleotides also are disclosed, particularly uses rela...