ALEXANDRIA, Va., Sept. 8 -- United States Patent no. 12,729,394, issued on Sept. 8, was assigned to Deutsches Krebsforschungszentrum (Heidelberg, Germany).

"Immune enhancers" was invented by Nikolaus Dietlein (Heidelberg, Germany) and Hans-Reimer Rodewald (Heidelberg, Germany).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to an inhibitor of ubiquitin-specific peptidase 22 (Usp22 inhibitor) for use in activation of an immune response in a subject and to a kit comprising said Usp22 inhibitor. The present invention further relates to methods for identifying a subject susceptible to treatment of disease by administration of a Usp22 inhibitor and for identifying a compound for activa...