ALEXANDRIA, Va., March 17 -- United States Patent no. 12,577,291, issued on March 17, was assigned to Deutsches Krebsforschungszentrum (Heidelberg, Germany).

"Means and methods for treating and diagnosing fibrosis or fibrosis-associated diseases" was invented by Amir Abdollahi (Heidelberg, Germany), Kashi Javaherian (Lexington, Mass.), Jurgen Debus (Heidelberg, Germany) and Cheng Zhou (Dossenheim, Germany).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention is concerned with a protein oligomer comprising (i) at least two NC-1 monomers of collagen 18 or (ii) at least two endostatin domains of collagen 18 or (iii) at least two N-terminal peptides of the collagen 18 endostatin domain, for use in...