US Patent Issued to DANA-FARBER CANCER INSTITUTE on Sept. 29 for "Potent and selective inhibitors of IRAK4" (Massachusetts Inventors)

ALEXANDRIA, Va., Sept. 30 -- United States Patent no. 12,747,228, issued on Sept. 29, was assigned to DANA-FARBER CANCER INSTITUTE INC. (Boston).

"Potent and selective inhibitors of IRAK4" was invented by John M. Hatcher (Boston) and Nathanael S. Gray (Jamaica Plain, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The disclosure relates to compounds that act as inhibitors of interleukin 1 (IL-1) receptor-associated kinase 4 (IRAK4); pharmaceutical compositions comprising the compounds; and methods of treating or preventing kinase-mediated disorders, including cancer and other proliferation diseases."

The patent was filed on Sept. 8, 2022, under Application No. 18/690,160.

*For further information, inc...