US Patent Issued to DANA-FARBER CANCER INSTITUTE on May 12 for "Methods of high-throughput identification of T cell epitopes by capturing cytokines on the surface of antigen-presenting cells" (Massachusetts Inventors)

ALEXANDRIA, Va., May 12 -- United States Patent no. 12,624,349, issued on May 12, was assigned to DANA-FARBER CANCER INSTITUTE INC. (Boston).

"Methods of high-throughput identification of T cell epitopes by capturing cytokines on the surface of antigen-presenting cells" was invented by Matthew Meyerson (Concord, Mass.) and Mark N. Lee (Arlington, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure relates to methods that combine identification of T cell-secreted cytokines by modified antigen-presenting cells (APCs), cell sorting, and next-generation sequencing to identify class I- and class II-restricted epitopes starting from massively-complex peptide-encoding oligonucleotide pools. ...