US Patent Issued to Dana-Farber Cancer Institute on May 12 for "Allosteric EGFR inhibitors and methods of use thereof" (Massachusetts Inventors)

ALEXANDRIA, Va., May 12 -- United States Patent no. 12,622,909, issued on May 12, was assigned to Dana-Farber Cancer Institute Inc. (Boston).

"Allosteric EGFR inhibitors and methods of use thereof" was invented by Nathanael S. Gray (Jamaica Plain, Mass.), David A. Scott (Newton, Mass.), Thomas Gero (Stow, Mass.), Michael Eck (Brookline, Mass.), David Heppner (Brookline, Mass.), Tyler Beyett (Brookline, Mass.) and Ciric To (Medford, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The disclosure relates to compounds that act as an allosteric inhibitors of epidermal growth factor receptor (EGFR); pharmaceutical compositions comprising the compounds; and methods of treating or preventing kinase-mediated dis...