US Patent Issued to Dana-Farber Cancer Institute on Aug. 4 for "Transcriptional enhanced associate domain (TEAD) transcription factor inhibitors and uses thereof" (Massachusetts Inventors)

ALEXANDRIA, Va., Aug. 5 -- United States Patent no. 12,698,259, issued on Aug. 4, was assigned to Dana-Farber Cancer Institute Inc. (Boston).

"Transcriptional enhanced associate domain (TEAD) transcription factor inhibitors and uses thereof" was invented by Nathanael S. Gray (Boston), Tinghu Zhang (Brookline, Mass.), Yao Liu (Brookline, Mass.), Mengyang Fan (Allston, Mass.) and Yang Gao (Boston).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided herein are compounds of Formula (I), and pharmaceutically acceptable salts, solvates, hydrates, polymorphs, co-crystals, tautomers, stereoisomers, isotopically labeled derivatives, prodrugs, compositions, and mixtures thereof. Also provided are methods and kits i...