US Patent Issued to Dana-Farber Cancer Institute, President and Fellows of Harvard College on Feb. 10 for "CGAS/DNCV-like nucleotidyltransferases and uses thereof" (Massachusetts Inventors)

ALEXANDRIA, Va., Feb. 11 -- United States Patent no. 12,545,900, issued on Feb. 10, was assigned to Dana-Farber Cancer Institute Inc. (Boston) and President and Fellows of Harvard College (Cambridge, Mass.).

"CGAS/DNCV-like nucleotidyltransferases and uses thereof" was invented by Aaron Whiteley (Brookline, Mass.), Philip J. Kranzusch (Brighton, Mass.), John Mekalanos (Newton, Mass.) and James Eaglesham (Boston).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention is based, in part, on the discovery and characterization of the CD-NTase family of proteins, as well as compositions comprising CD-NTases, methods of producing nucleotide-based second messengers using such polypeptides, and methods o...