US Patent Issued to CytoSite Biopharma on Feb. 17 for "Granzyme B directed imaging and therapy" (Indiana, Massachusetts Inventors)

ALEXANDRIA, Va., Feb. 17 -- United States Patent no. 12,551,582, issued on Feb. 17, was assigned to CytoSite Biopharma Inc. (Boston).

"Granzyme B directed imaging and therapy" was invented by Julia Marie Clay (Indianapolis), Hui Xiong (Indianapolis), Kevin Michael Ruley (Indianapolis), Francisco A. Valenzuela (Indianapolis), Adam T. Hoye (Indianapolis), Mark A. Castanares (Indianapolis) and James Kronauge (Sudbury, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Compounds of Formula (I) and Formula (II), which are capable of binding to granzyme B. Also provided herein are pharmaceutical compositions comprising such for use in, for example, imaging Granzyme B and/or treating immunoregulatory abnormalitie...