ALEXANDRIA, Va., June 9 -- United States Patent no. 12,649,729, issued on June 9, was assigned to CYTOKINETICS INC. (South San Francisco, Calif.).

"Pyrazole derivatives useful as NAMPT modulators" was invented by Minxing Shen (San Bruno, Calif.), Antonio Romero (San Mateo, Calif.) and Pu-Ping Lu (Foster City, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided herein are compounds of formula (A): or a pharmaceutically acceptable salt thereof, wherein X, R1, R2, R3, R4, Ry, and Rz are as defined herein. Also provided herein is a pharmaceutically acceptable composition comprising a compound of formula (A), or a pharmaceutically acceptable salt thereof, as well as methods of using a compound of formu...