US Patent Issued to CRISPR Therapeutics on Aug. 4 for "Manufacturing process for making t cells expressing chimeric antigen receptors" (Massachusetts Inventors)

ALEXANDRIA, Va., Aug. 5 -- United States Patent no. 12,698,317, issued on Aug. 4, was assigned to CRISPR Therapeutics AG (Zug, Switzerland).

"Manufacturing process for making t cells expressing chimeric antigen receptors" was invented by Hui Yu (Cambridge, Mass.), Demetrios Kalaitzidis (Cambridge, Mass.) and Siyuan Tan (Cambridge, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Aspects of the present disclosure relate to methods for manufacturing genetically engineered T cells expressing a chimeric antigen receptor (CAR) that provide several improvements over conventional manufacturing methods, thereby enabling production of a robust supply of clinically useful CAR T-cell therapies."

The patent was fil...