ALEXANDRIA, Va., Aug. 5 -- United States Patent no. 12,697,397, issued on Aug. 4, was assigned to Coave Therapeutics (Paris).

"Modified adeno-associated virus vectors and delivery thereof into the central nervous system" was invented by Philippe Moullier (San Sebastian, Spain) and Willem Broekaert (Dilbeek, Belgium).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to modified adeno-associated virus (AAV) vectors for use in transducing a cell in the central nervous system (CNS) of a subject, and for use in the prevention or treatment of a CNS disease. In particular, the modified AAV vectors according to the present invention comprise at least one surface-bound saccharide, and are to...