ALEXANDRIA, Va., March 31 -- United States Patent no. 12,589,083, issued on March 31, was assigned to CLEXIO BIOSCIENCES LTD. (Yokne'am, Israel).

"Abuse-deterrent dosage forms containing esketamine" was invented by Derek Moe (Mound, Minn.), Randal Seburg (Louisville, Ky.) and Sagar Rane (Bellevue, Wash.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed herein are immediate release oral dosage forms that contain abuse-deterrent and abuse-resistant features. In particular, the disclosed dosage forms can provide deterrence of abuse by ingestion of multiple individual doses. The disclosed dosage forms can likewise provide protection from overdose in the event of accidental or intentional ingestion of mult...