ALEXANDRIA, Va., June 2 -- United States Patent no. 12,642,828, issued on June 2, was assigned to Claudio De Simone (Chateau d'Oex, Switzerland).

"Use of bacterial compositions in the treatment and prophylaxis of airway diseases" was invented by Claudio De Simone (Chateau d'Oex, Switzerland).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to the use of bacterial compositions having an arginine deiminase activity (inhibition of nitric oxide synthase by conversion of L-arginine to L-citrulline) of 1-1,000 micro metreol L-citrulline/h/g composition and a sphingomyelinase (ceramide generation) activity of 0.01-1.000 nmoles ceramides/h/g composition in the treatment and/or prophylaxis ...