ALEXANDRIA, Va., May 12 -- United States Patent no. 12,624,359, issued on May 12, was assigned to CITY UNIVERSITY OF HONG KONG (Kowloon, Hong Kong).
"L-RNA aptamers and methods of identifying the same" was invented by Chun Kit Kwok (Kowloon, Hong Kong) and Danyang Ji (Kowloon, Hong Kong).
According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed herein is a method of identifying an L-RNA aptamer specific for a target nucleic acid. According to some embodiments of the present disclosure, the method comprises, in vitro transcribing the DNAs of the DNA library into D-RNAs, followed by identifying target-specific D-RNAs via negative and positive selections, and then producing the L-RNA aptamer based on the identifi...