US Patent Issued to CITY OF HOPE on March 31 for "Oncolytic virus compositions including IL-15 complex and methods for the treatment of cancer" (California Inventors)

ALEXANDRIA, Va., March 31 -- United States Patent no. 12,589,112, issued on March 31, was assigned to CITY OF HOPE (Duarte, Calif.).

"Oncolytic virus compositions including IL-15 complex and methods for the treatment of cancer" was invented by Jianhua Yu (Duarte, Calif.) and Michael A. Caligiuri (Pasadena, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided herein, inter alia, are compositions and methods including recombinant oncolytic viruses expressing human IL-15 and human IL-15RAlpha-sushi domain for the treatment of cancer and immune disorders. The recombinant oncolytic viruses may be used in combination with immune cells expressing chimeric antigen receptors (CAR) targeting EGFR and EGFR mu...