ALEXANDRIA, Va., March 3 -- United States Patent no. 12,565,658, issued on March 3, was assigned to City of Hope (Duarte, Calif.).

"CD33 targeted chimeric antigen receptor modified T cells for treatment of CD33 positive malignancies" was invented by Tongyuan Xue (Duarte, Calif.), David A. Horne (Duarte, Calif.), Lihua Elizabeth Budde (Duarte, Calif.), Stephen Forman (Duarte, Calif.) and Marissa M. Del Real (Duarte, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Chimeric antigen receptors targeted to CD33 are described together with their use in treating various cancers and in reducing myeloid derived suppressor cells in a patient."

The patent was filed on June 1, 2020, under Application No. 17/614,23...