US Patent Issued to City of Hope, California Institute of Technology on July 7 for "Conditional-siRNAs and uses thereof in treating acute myeloid leukemia" (California Inventors)

ALEXANDRIA, Va., July 7 -- United States Patent no. 12,674,164, issued on July 7, was assigned to City of Hope (Duarte, Calif.) and California Institute of Technology (Pasadena, Calif.).

"Conditional-siRNAs and uses thereof in treating acute myeloid leukemia" was invented by Guido Marcucci (Duarte, Calif.), Ya-Huei Kuo (Duarte, Calif.), Si-Ping Han (Duarte, Calif.), Lisa Scherer (Duarte, Calif.), William A. Goddard III (Pasadena, Calif.) and John Rossi (Duarte, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed herein are conditional siRNAs activatable by CBFBeta-MYH11 oncogenic gene and use thereof for treating conditions such as acute myeloid leukemia (AML). The conditional siRNAs target MCL-1...